The CRPP Synapse, Trauma, and Addiction is a consortium uniting researchers from multiple disciplines to address critical challenges in the understanding and treatment of trauma spectrum and substance use disorders with focus on memory. The consortium is led by Prof Birgit Kleim and Prof Boris Quednow. Three PIs are currently contributing to the work, Prof Birgit Kleim, Prof Boris Quednow, both involved in the Human Workpackage, and Prof Judith Homberg, in the lead of the Animal Workpackage. The CRPP has an international advisory board.